Structure and properties of CY5-NH2 Cyanine5-amine

CY5-NH2 is a dye with fluorescent properties and it is a member of the Cyanine family. The structure and properties of CY5-NH2 are described in detail below:

Structure:

The chemical name of CY5-NH2 is 1-(2-Carboxyethyl)-1,2,3,3-tetramethylindotricarbocyanine, 4-aminobutyric acid salt.Its chemical structure consists of a central heterocyclic structure and two benzene rings.The central heterocyclic structure of CY5-NH2 consists of The central heterocyclic structure of CY5-NH2 consists of a five-membered heterocyclic ring containing nitrogen atoms and a seven-membered heterocyclic ring containing nitrogen and sulfur atoms. These two heterocycles are linked together by a conjugated structure to form a conjugated system, which gives CY5-NH2 its fluorescent properties.

Nature:

1. Fluorescent properties: CY5-NH2 has strong fluorescent properties and can emit fluorescence in the infrared wavelength range. Its maximum absorption wavelength is 649 nm and its maximum emission wavelength is 670 nm.This gives CY5-NH2 good fluorescence stability and signal intensity in the near-infrared (NIR) spectral range, making it suitable for bio-imaging and detection applications.

2. Chemical stability: CY5-NH2 has good chemical stability and can maintain its fluorescent properties in living organisms or in complex chemical environments. This makes CY5-NH2 a commonly used biomarker tool for the detection, imaging and localization of biomolecules.

3. Water solubility: CY5-NH2 is usually present as a hydrochloride or other salt, giving it good water solubility. This allows CY5-NH2 to be easily used in biological systems and to interact with water-soluble biomolecules.

4. Biocompatibility: CY5-NH2 is biocompatible with most biological systems at appropriate concentrations. However, it is important to note that high concentrations of CY5-NH2 may have toxic effects on cells or animals, so careful control of concentration and dosage is needed when using it.

In conclusion, CY5-NH2 is a dye with fluorescent properties, chemical stability and water solubility. It can be used in applications such as fluorescent labeling of biomolecules, fluorescent imaging and detection. When using CY5-NH2, care needs to be taken to control the concentration and dosage to ensure its biocompatibility and safety in biological systems.