Isothiocyanate-Polyethylene Glycol-Amino FITC-PEG-NH2 MW:5000 Carboxylic group Covalent bonding Highly selective Surface modification

FITC-PEG-NH2 is a widely used material in the biomedical field consisting of fluorescent isothiocyanate (FITC), polyethylene glycol (PEG), and amino group (NH2).

1. Fluorescent labeling: FITC-PEG-NH2 is widely used for fluorescent labeling of biomolecules. For example, it can form a covalent bond with the carboxyl group (COOH) in proteins or antibodies, thus causing the target molecule to acquire fluorescence. Such labeled molecules can be detected in a fluorescence microscope or flow cytometer to track and study the behavior and distribution of these molecules in cells or in vivo.

2. Drug delivery: FITC-PEG-NH2 can also be used in the construction of drug carriers. For example, it can be bound to drug molecules or nanoparticles to improve the stability and solubility of the drug in vivo via PEG, while fluorescent labeling using FITC can be used to track the release and distribution of the drug.

3. Cell engineering: FITC-PEG-NH2 can be used for cell surface modification to alter cell properties. For example, by reacting with specific sites of cell surface molecules, properties such as adhesion and immunity can be altered, or specific functional molecules can be introduced to the cell surface.

4. Biosensors: FITC-PEG-NH2 can be used for the preparation of biosensors. For example, it can form a self-assembled monolayer with the electrode surface, and through the fluorescence change of FITC, high sensitivity and high selectivity detection of specific biomolecules can be realized.

Therefore, FITC-PEG-NH2 has a wide range of applications and is an important tool in modern biomedical research.