Application of FITC-PEG-MAL Fluorescent isothiocyanate-polyethylene glycol-maleimide Biomolecule modification MW:3400

FITC-PEG-MAL is a commonly used biomedical material that consists of three components: fluorescent isothiocyanate (FITC), polyethylene glycol (PEG) and maleimide (MAL).

1. Fluorescent isothiocyanate (FITC): FITC is a commonly used fluorescent dye for labeling proteins, nucleic acids, and other biomolecules and can be detected under a fluorescence microscope or flow cytometer.FITC has excellent fluorescence stability and high fluorescence quantum yield.

2. Polyethylene Glycol (PEG): PEG is a commonly used biocompatible material with good water solubility, which increases the solubility and stability of the molecule and reduces immune reactions and protein adsorption. In addition, PEG can increase the in vivo half-life of a molecule, thereby improving the efficacy of a drug.

3. Maleimide (MAL): MAL is a commonly used bioactive molecule that reacts with molecules containing sulfhydryl groups (SH), such as cysteine, to achieve specific modification and functionalization of biomolecules.

The applications of FITC-PEG-MAL include the following:

1. Fluorescent labeling: Due to the fluorescent nature of FITC, FITC-PEG-MAL can be used for fluorescent labeling of proteins, nucleic acids and other biomolecules.

2. Modification of biomolecules: Due to the activity of MAL, FITC-PEG-MAL can be used for the specific modification and functionalization of biomolecules containing sulfhydryl groups.

3. Drug delivery: FITC-PEG-MAL can be used for solubility enhancement and targeted drug delivery due to the biocompatibility and solubilizing properties of PEG.

Overall, FITC-PEG-MAL is a multifunctional biomedical material with broad application prospects.