Application of ICG-NH2 in cell tracing and tracking ICG-amine CAS1686147-55-6 Cell migration Cell localization

ICG-NH2, as a derivative of ICG-amine, has a wide range of applications in cell tracing and tracking. By labeling ICG-NH2 on the surface or inside of cells, the migration, localization and function of cells can be observed and tracked by near-infrared fluorescence imaging. Below are several important applications of ICG-NH2 in cell tracing and tracking and corresponding examples:

1. Stem cell tracing: ICG-NH2 can be used for tracing and tracking of stem cells. Researchers can label ICG-NH2 on the surface or inside of stem cells, observe the localization and homing ability of stem cells through near-infrared fluorescence imaging, and assess the effect of stem cell therapy. For example, in heart regeneration research, ICG-NH2 can be labeled on the surface of stem cells, and the localization and differentiation of stem cells within damaged heart tissues can be observed by NIR fluorescence imaging.

2. Cell migration and metastasis: ICG-NH2 can be used to observe cell migration and metastasis. Researchers can label ICG-NH2 on the surface or inside of cells, observe the migration and metastasis process of cells through near-infrared fluorescence imaging, and study the movement mechanism and metastasis pathway of cells. For example, in tumor metastasis research, ICG-NH2 can be labeled on the surface of tumor cells, and the migration and metastasis process of tumor cells can be observed by near-infrared fluorescence imaging technology to study the metastasis mechanism of tumors.

3. Cell localization and function: ICG-NH2 can be used to observe cell localization and function. Researchers can label ICG-NH2 on the surface or inside of cells, observe the cellular localization and function through near-infrared fluorescence imaging, and study the role and response mechanism of cells. For example, in neuroscience research, ICG-NH2 can be labeled on the surface of neurons, and the localization and function of neurons can be observed by near-infrared fluorescence imaging to study neuronal signaling and the formation of neural networks.

In conclusion, ICG-NH2, as a derivative of ICG-amine, has a wide range of applications in cell tracing and tracking. By labeling ICG-NH2 on the cell surface or inside, the migration, localization and function of cells can be observed and tracked by near-infrared fluorescence imaging, which allows in-depth study of the biological processes and functions of cells.