Structure and properties of CY7-NH2 Cyanine7-amine

Cyanine7-NH2 is a Cyanine7 dye with an amino group (-NH2). Its chemical structure is shown below:

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H3C--CH=CH--N(CH3)2--C6H4--CH=CH--C6H4--N(CH3)2--CH=CH--C6H4--CH=CH--C6H4--NH2

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Cyanine 7-NH2 has several characteristics and properties:

1. Fluorescent properties: Cyanine7-NH2 has strong fluorescent properties, with a maximum excitation wavelength of about 750 nm and a maximum emission wavelength of about 773 nm, which makes it emit fluorescence in the near-infrared spectral range, which is favorable for optical imaging and analysis in living organisms.

2. Solubility: Cyanine7-NH2 has good solubility in a number of organic solvents (e.g. methanol, dimethyl sulfoxide, etc.) and water. This makes it has a better application prospect in biomolecular labeling and analysis.

3. Reactivity: The amino group (-NH2) on Cyanine7-NH2 is reactive and can be used for covalent coupling or chemical reactions with other molecules. For example, it can be combined with carboxylated or acidic compounds to prepare specific markers or probes through amino activation reactions.

4. Stability: Cyanine 7-NH2 has good stability and can be stored for long periods of time and maintain its fluorescent properties under appropriate conditions. It is also highly stable to light and heat, making it suitable for long term use in optical imaging and analysis.

In conclusion, Cyanine7-NH2 is a Cyanine7 dye with an amino group that has strong fluorescent properties, good solubility and stability. It can be used in near-infrared optical imaging and analysis, and can also be coupled with other molecules through chemical reactions for biomolecular labeling and probe preparation.