CY5.5 in Near Infrared Imaging Cyanine5.5 Tumor Imaging Vascular Imaging
The application of Cyanine 5.5 (Cy5.5) in near-infrared (NIR) imaging is primarily utilized for imaging and detection in organisms or tissues by taking advantage of its longer wavelength and higher fluorescence stability. This application is often referred to as near infrared fluorescence imaging (NIRF) or optical imaging. The following are applications of Cy5.5 in NIRF imaging:
1. Tumor imaging:
Labeling Cy5.5 on a tumor-targeting probe can be used for tumor imaging. For example, labeling Cy5.5 on a tumor-associated antibody, peptide, or small molecule-targeted probe enables localization and imaging of a tumor by injecting the probe and using near-infrared laser excitation. Such applications can be used for early tumor diagnosis, tumor treatment monitoring and tumor imaging navigation.
2. Vascular imaging:
Labeling Cy5.5 on a vascular targeting probe can be used for vascular imaging. For example, labeling Cy5.5 on a vascular-specific antibody or small molecule-targeted probe allows localization and imaging of blood vessels by injecting the probe and using near-infrared laser excitation. Such applications can be used for vascular lesion detection, vascular function studies, and vascular imaging navigation.
3. Lymph node imaging:
Labeling Cy5.5 on a lymph node-targeting probe can be used for lymph node imaging. For example, labeling Cy5.5 on a lymph node-specific antibody or small molecule-targeted probe enables localization and imaging of lymph nodes by injecting the probe and using near-infrared laser excitation. This application can be used for lymph node tumor metastasis detection, lymphatic circulation studies, and lymph node imaging navigation.
4. Brain imaging:
Labeling Cy5.5 on a brain-targeting probe can be used for brain imaging. For example, labeling Cy5.5 on a brain-specific antibody or small molecule-targeted probe, by injecting the probe and using near-infrared laser excitation, can enable localization and imaging of the brain. Such applications can be used for brain tumor detection, cerebrovascular function studies, and brain region imaging navigation.
In summary, Cyanine5.5 can be used in near infrared imaging for tumor imaging, vascular imaging, lymph node imaging and brain imaging. By labeling Cy5.5 on specific targeting probes, localization, visualization and monitoring of target areas in organisms or tissues can be achieved. Such applications can help researchers understand disease development, biological processes and drug treatment effects, among others. By combining different experimental techniques and imaging methods, quantitative, localization and functional studies of specific regions can be achieved.
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