Brand | YUSI | ||
---|---|---|---|
English name | 2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine | ||
Chinese alias | Dlin-KC2-DMA;2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine | ||
Technical index | ≥95% | ||
CAS | 1190197-97-7 | Product number | |
Molecular formula | C43H79NO2 | Molecular weight | 642.1 g/mol |
Product number | Specifications | Price | Stock |
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Product Structure:
2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Size :
1g(Specifications can be customized)
Product details:
Dlin-KC2-DMA is a lipid-based compound used in the development of lipid nanoparticles (LNPs) for the delivery of nucleic acids, such as mRNA.
In terms of structure, Dlin-KC2-DMA consists of a cationic lipid core, which contains two hydrocarbon chains that provide hydrophobic properties, allowing it to form stable lipid bilayers. These lipid bilayers are essential for encapsulating and protecting the mRNA payload during delivery.
Dlin-KC2-DMA has a moderate solubility in polar solvents, such as ethanol and dimethyl sulfoxide (DMSO). However, its solubility may vary depending on the specific formulation and experimental conditions.
The stability of Dlin-KC2-DMA is critical for maintaining the integrity and efficacy of the lipid nanoparticles. It exhibits good stability under physiological conditions, ensuring the long-term shelf life and viability of the mRNA-loaded LNPs. However, it is important to note that the stability of Dlin-KC2-DMA can be influenced by factors such as temperature, pH, and exposure to certain chemicals, which may affect the overall performance and functionality of the LNPs.
Description:
Dlin-KC2-DMA is a novel lipid-based compound used in the development of lipid nanoparticles (LNPs) for the delivery of mRNA-based vaccines and therapeutics. It serves as an ionizable cationic lipid, meaning it can be positively charged at certain pH levels, facilitating the encapsulation of negatively charged mRNA molecules.
The main characteristics of Dlin-KC2-DMA include its ability to form stable LNPs with high encapsulation efficiency, which is crucial for protecting and delivering the mRNA payload. It has been shown to have a low toxicity profile, making it suitable for use in clinical applications.
Furthermore, Dlin-KC2-DMA has demonstrated excellent in vitro and in vivo transfection efficiency, allowing for efficient delivery of mRNA to target cells and subsequent protein expression. This property is essential for the successful development of mRNA-based vaccines and therapies.
Overall, Dlin-KC2-DMA's unique properties, including its stability, low toxicity, and high transfection efficiency, make it a promising component for the development of efficient and safe mRNA delivery systems.
Storage conditions:
Store at - 20 ℃. Avoid frequent thawing and freezing.
Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.
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