Product Structure:

DOTAP；1,2-Dioleoyloxy-3-(trimethylammonium)propane

Size :

500mg;1g（Specifications can be customized）

Product details: 

Solubility: DOTAP is soluble in organic solvents such as chloroform, methanol, and ethanol. However, it is poorly soluble in water due to its hydrophobic nature. To prepare liposomes, DOTAP is typically dissolved in an organic solvent and then hydrated with an aqueous solution to form liposomes.

Stability: DOTAP liposomes are generally stable under physiological conditions. However, their stability can be affected by various factors such as temperature, pH, and presence of ions. The presence of divalent cations, such as calcium, can induce liposome aggregation or fusion. It is important to optimize the formulation and storage conditions to maintain the stability of DOTAP liposomes. 

Storage conditions: DOTAP liposomes should be stored at a temperature below the phase transition temperature of the lipid to prevent aggregation or leakage. Typically, they are stored at 4°C or below to maintain their stability. It is also recommended to protect the liposomes from light exposure and avoid repeated freeze-thaw cycles, as these can negatively affect the stability of the liposomes.

Description:

DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid commonly used in biomedical research and drug delivery applications. It is characterized by its positive charge, which allows it to interact with negatively charged molecules such as nucleic acids and cell membranes. DOTAP can form lipid bilayers or liposomes in aqueous solutions, making it an effective delivery vehicle for nucleic acids and other cargo. Its ability to disrupt cell membranes and its biocompatibility make it suitable for use in gene therapy and other biomedical applications.

Storage conditions:

Store at - 20 ℃. Avoid frequent thawing and freezing.

Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.

Based on the business model of independent research and development, production and sales integration, the company's products have obvious price advantages compared with similar products on the market. In addition, we also provide professional product customization services.

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