FITC-PEG-Alkyne Isothiocyanate-Polyethylene Glycol-Alkyne MW:1000 click reaction Molecular labeling Biosensing Nanotechnology
FITC-PEG-Alkyne is a fluorescently labeled polyethylene glycol (PEG) compound that has a wide range of applications in biochemical and biomedical research. This compound consists of three main components: fluorescent isothiocyanate (FITC), polyethylene glycol (PEG), and an alkyne group.
FITC is a commonly used fluorescent probe that is widely used in fluorescence microscopy, flow cytometry, and other techniques. Its fluorescence emission is in the green light region, allowing the compound to produce high-contrast images in many biological tissues and cells.
PEG is an extremely biocompatible polymer that improves drug solubility, extends the half-life of drugs in the body, reduces immunogenicity and increases drug stability.
An alkyne group is a chemical group that can be linked to another functionalized compound by click chemistry.
Here are some applications of FITC-PEG-Alkyne:
1. Biomarkers: FITC-PEG-Alkyne can be used to label a variety of biomolecules such as proteins, peptides, antibodies, etc. for detection and tracking in fluorescence microscopy or flow cytometry. For example, a researcher can use FITC-PEG-Alkyne to label antibodies in order to detect specific proteins in cell or tissue samples.
2. Drug delivery: FITC-PEG-Alkyne can be used to prepare fluorescently labeled drug delivery systems. For example, researchers can prepare fluorescently labeled drug nanoparticles by linking FITC-PEG-Alkyne with drug molecules via click chemistry. These fluorescently labeled drug nanoparticles can be tracked under a fluorescence microscope to study the distribution and metabolism of the drug in the body.
3. Biosensing: FITC-PEG-Alkyne can be utilized to prepare fluorescent biosensors. For example, researchers can connect FITC-PEG-Alkyne with specific biorecognition elements (e.g., antibodies, proteins, peptides, nucleic acids, etc.) via click chemistry to prepare fluorescent sensors capable of highly sensitive detection of specific molecules.
4. Nanotechnology: FITC-PEG-Alkyne can be used to prepare fluorescently labeled nanomaterials. For example, researchers can prepare fluorescently labeled nanoparticles by linking FITC-PEG-Alkyne with nanoparticles through click chemistry. These fluorescently labeled nanoparticles can be tracked under a fluorescence microscope to study the distribution and behavior of the nanomaterials in vivo.