Product name：

Chinese name: PLGA-PEG-PLGA

English name: (D, L-lactide co glycolide) Polyethylene glycol (D, L-lactide co glycolide)

Product packaging：

1g (specification can be customized according to requirements)

Product details：

Solvent: Conventional organic solvents such as chloroform, dichloromethane, acetone, DMF, DMSO, etc.

Character: White/almost white solid powder or semi solid based on different molecular weights.

Stability: Freeze stored under dry and dark conditions to avoid repeated freeze-thaw.

Molecular weight (PEG): 2000, 3400, 5000, other molecular weights can be customized.

Molecular weight (PLGA): customized between 5000 and 30000

PLGA specification: 75:25 or 50:50

To ensure the stability of the product, please note that the packaging can only be opened and used after constant temperature drying!

Product description：

PLGA-PEG-PLGA is an amphiphilic BAB triblock copolymer composed of hydrophilic block polyethylene glycol (PEG) and hydrophobic block polylactide glycolide (PLGA). Because of its excellent performance, it can be used to make biodegradable temperature sensitive hydrogel; Polyethylene glycol copolymers with biodegradable and biocompatible polyester segments can also be used to prepare core-shell micelles, nanoparticles, and microspheres. The active groups at the end of PLGA-PEG-PLGA can link to some modified peptides, proteins, sugars, folate, or antibodies, making them actively targeted. PEG-PLGA can be dissolved in a series of common organic solvents, depending on its composition, especially the ratio of LA to GA and the total molecular weight of PLGA. With the increase of molecular weight and GA content, its solubility in ordinary organic solvents deteriorates. Usually, PEG-PLGA with lower molecular weight or higher LA content can be more easily soluble in chlorinated solvents such as dichloromethane or chloroform.

Polylactic acid glycolic acid (PLGA) is a copolymer formed by the polymerization reaction of lactic acid (LA) and glycolic acid (GA). It is an important biodegradable material with non-toxic and good biocompatibility characteristics, and has been increasingly widely used in fields such as drug delivery, gene therapy, and medical fiber materials; And it has been certified by the US Food and Drug Administration (FDA) and officially included as a medicinal excipient in the US Pharmacopoeia.

PLGA can copolymerize with PEG blocks to form diblock, triblock, or even tetrablock copolymers, which can be used for micelles, drug encapsulation, drug delivery, and sustained release control. The active group of PLA PEG with MALmaleimide can modify proteins, antibodies, and other small molecule materials. MALs can react with SH thiols, and NHS in PLGA-PEG-NHS can react with amino groups to connect with small molecule materials such as antibodies and proteins.

PLGA-PEG-PLGA is sensitive to light and temperature, and for optimal use, the material should always be kept dry at low temperatures to avoid frequent thawing and freezing.

PLGA-PEG-PLGA should be stored at a low temperature below 4 ℃, away from light, and dry. The material can be treated under inert gas to achieve optimal stability, and retested after 12 months.

Note: The products sold by our company are only for scientific research and cannot be used for human experiments or treatment.

The official website of Chongqing Yusi Pharmaceutical Technology Co., Ltd. showcases Yusi Pharmaceutical's business model based on independent research and development, production, and sales integration. Compared with similar products in the market, the company's products have a significant price advantage. In addition, we also provide professional product customization services.

Please contact us for other products:

Telephone: 023-62795528

Customer service hotline: 18896157519, QQ: 3354316092

19923757617, QQ: 3279537175

17725012670, QQ: 3492925539

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