Product Structure:

DTAB;Dodecyltrimethylammonium bromide

Size :

1g（Specifications can be customized）

Product details:

Solubility:DTAB is soluble in water up to certain concentrations. However, at higher concentrations, it may exhibit limited solubility and form aggregates due to strong intermolecular interactions. This can result in reduced stability and altered properties of the lipid-based systems.

Stability:To enhance the stability of DTAB-based lipid systems, various strategies can be employed. These include adjusting the pH of the solution, using co-surfactants or co-solvents to increase solubility, and optimizing the formulation composition. It is important to note that excessive heat, extreme pH conditions, or presence of incompatible excipients can lead to destabilization of DTAB-based systems.

Storage conditions:DTAB should be stored in a cool and dry place, away from direct sunlight. It is recommended to store DTAB in sealed containers to prevent moisture absorption and maintain its stability. Additionally, it is advisable to avoid temperature fluctuations during storage to minimize the risk of lipid oxidation or degradation.

Description:

DTAB, short for Dodecyltrimethylammonium bromide, is a cationic lipid commonly used in the formulation of liposomes. Cationic lipids like DTAB have a positively charged headgroup, which allows them to interact with negatively charged molecules, such as nucleic acids, proteins, and cell membranes.

DTAB is synthesized from dodecylamine and trimethylamine, and its structure consists of a hydrophobic tail and a hydrophilic headgroup. The hydrophobic tail is made up of a 12-carbon chain, while the hydrophilic headgroup contains a positively charged quaternary ammonium group.

In liposome formulations, DTAB can be used as a primary or co-lipid to impart positive charge to the liposomes. The positive charge allows for electrostatic interactions with negatively charged molecules, facilitating their encapsulation or binding to the liposomes. This property makes DTAB liposomes particularly useful for gene and drug delivery applications.

Storage conditions:

Store at - 20 ℃. Avoid frequent thawing and freezing.

Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.

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