Product Structure:

DSPE-PEG-Transferrin

Size :

1g（Specifications can be customized）

Product details:

Solvent: water, methanol, chloroform, DMF, DMSO and other conventional organic solvents.

Properties: White / off white solid powder or viscous liquid based on different molecular weights.

Stability: cold storage, avoid repeated freezing and thawing.

Reactive group: primary amine (- NH2)

Lipid type: 18C PE, saturated

Molecular weight (PEG): 2000, 3400, 5000, other molecular weights can be customized.

In order to ensure the stability of the product, please note that the package can only be opened for use after constant temperature drying!

Description:

The transferrin receptor (TfR) is a transmembrane glycoprotein whose function is to mediate iron absorption through its interaction with transferrin. In normal cells, the expression level of the receptor is low, and the expression of the transferrin receptor in cells (chronic lymphocytic non-Hodgkin tumors) is significantly increased due to the increased demand for iron in rapidly growing cells [2-4]. At present, two transferrin receptors, TfR1 and TfR2, have been found, both of which are type II transmembrane glycoproteins that bind to transferrin and mediate iron absorption. TfR1 is expressed in many cells (such as red blood cells, hepatocytes, monocytes), and can change its conformation according to the change of environmental pH, and convert the results of conformational change into a change in the binding strength of transferrin. TfR2 is mainly expressed in the liver, and its main function may be to regulate and maintain the homeostasis of iron ions in the body, while its role in transporting iron ions to rapidly dividing tissues is weak. Using the effective targeting function of transferrin receptor, the cross-linking of transferrin and drugs can improve the specific binding ability of drugs, but also improve the effect.

Storage conditions:

Store at - 20 ℃. Avoid frequent thawing and freezing.

Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.

Based on the business model of independent research and development, production and sales integration, the company's products have obvious price advantages compared with similar products on the market. In addition, we also provide professional product customization services.

For other products, please contact us:

Telephone: 023-62795528

Customer service hotline: 

18896157519，QQ: 3354316092

19923757617，QQ：3279537175

17725012670，QQ：3492925539