Cyanine7 in biomedical imaging Nanoparticles Tissue metabolism
The application of Cyanine7 in biomedical imaging is mainly by labeling it on nanoparticles or drug-carrying systems for near-infrared fluorescence imaging to study structural, functional and metabolic processes in organisms. Here are some applications of Cyanine7 in biomedical imaging:
1. Tumor imaging: Cyanine7 is labeled on anti-tumor drugs or nanoparticles and used for near-infrared fluorescence imaging by targeting tumor tissues to track the distribution and release kinetics of the drug in the body. For example, Cyanine7 is labeled on nanoparticles of an antitumor drug for near-infrared fluorescence imaging of tumor growth and therapeutic effects.
2. Vascular imaging: Cyanine7 is labeled on nanoparticles or antibodies for near-infrared fluorescence imaging of the morphology and hemodynamics of blood vessels. For example, Cyanine7 is labeled on an anti-vascular endothelial cell antibody for NIR fluorescence imaging of the distribution and function of vascular endothelial cells.
3. Neuroimaging: Cyanine7 is labeled on neural-specific markers or neurotransmitter probes for near-infrared fluorescence imaging of neuronal activity and connectivity. For example, Cyanine7 is labeled on a neurotransmitter probe for NIR fluorescence imaging of neurotransmitter release and signaling in neurons.
4. Imaging of cancer metastasis: Cyanine7 is labeled on nanoparticles or antibodies for near-infrared fluorescence imaging of the processes and mechanisms of cancer metastasis. For example, Cyanine7 is labeled on antibodies against cancer stem cells for NIR fluorescence imaging of the origin and spread of cancer metastasis.
In conclusion, Cyanine7 has a wide range of applications in biomedical imaging and can be used in experiments such as tumor imaging, vascular imaging, neuroimaging and cancer metastasis imaging. By labeling Cyanine7 on nanoparticles or drug-carrying systems, high-resolution observation and quantitative analysis of specific structures and molecules in organisms can be achieved. Due to the near-infrared fluorescence properties of Cyanine7, it can be used for biomedical imaging under lower background signal conditions, improving the sensitivity and resolution of imaging.
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