Cyanine7 for tissue staining and imaging Vascular markers Tissue imaging
The application of Cyanine7 in tissue staining and imaging is mainly used to study the structure, composition and function of tissues by labeling it on specific ligands or antibodies. Below are some applications of Cyanine7 in tissue staining and imaging:
1. Immunotissue staining: Cyanine7 is labeled on specific antibodies and used for immunotissue staining to observe the localization and expression of specific proteins in tissues. For example, Cyanine7 is labeled on an anti-myocardin antibody and used to stain myofibers in cardiac muscle tissue to study myocardial structure and function.
2. Staining of tissue sections: Cyanine7 is labeled with specific ligands and used to stain tissue sections to visualize specific molecules or structures in the tissue. For example, Cyanine7 is labeled on ligands of nucleic acid dyes and used to stain DNA or RNA in tissue sections to study gene expression and cell function.
3. Vascular labeling: Cyanine7 is labeled on specific antibodies or ligands for the labeling of blood vessels to study the structure and function of blood vessels. For example, Cyanine7 is labeled on an anti-vascular endothelial cell antibody and used to stain vascular endothelial cells in tissues to observe the morphology and hemodynamics of blood vessels.
4. Tissue imaging: Cyanine7 is labeled on nanoparticles or drug-carrying systems and used for near-infrared fluorescence imaging to study the structure and function of tissues by targeting specific tissues or cells. For example, Cyanine7 is labeled on nanoparticles for targeting tumor tissues for fluorescence imaging and quantitative analysis of tumors.
In conclusion, Cyanine7 has a wide range of applications in tissue staining and imaging, and can be used in experiments such as immunotissue staining, tissue section staining, vascular labeling and tissue imaging. By labeling Cyanine7 on specific ligands or antibodies, high-resolution observation and quantitative analysis of specific structures and molecules in tissues can be achieved. Due to the near-infrared fluorescence property of Cyanine7, it can be used for tissue fluorescence imaging under the condition of lower background signal, which improves the sensitivity and resolution of imaging.
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