Product name:

CHO-PEG-CHO、ALD-PEG-ALD

Saze :

1g（Specifications can be customized）

Product details:

Properties: Based on different molecular weights, it is white / almost white solid or viscous liquid.

Solvent: water, chloroform, DMSO, dichloromethane and other conventional organic solvents.

Stability: cold storage, avoid repeated freezing and thawing.

Molecular weight (PEG): 2000, 3400, 5000, other molecular weights can be customized.

In order to ensure the stability of the product, please note that the package can only be opened for use after constant temperature drying!

Description:

Aldehyde peg is an amine reactive peg derivative, which can be used to modify biomolecules through available amine groups. An intermediate Schiff base is produced by the reaction between the ε - amine of aldehyde group and lysine residue and the α - amine of N-terminal. A stable CN bond will be formed by further reduction with hydride. Peg aldehydes react with amines at pH 5.5 to 9.5. Higher pH value will lead to multiple PEGylation of the terminal and lysine groups. Aldehyde peg is a common peg reagent for N-terminal PEGylation of protein or peptide.

Handlingand Use:

The target substance was dissolved in polyethylene glycol buffer solution. The concentration of primary amine group on the target material was estimated. Peg aldehyde stock solution was added to the target conjugate, and the final concentration was maintained at least 10 mg / ml. The mixture was stirred at room temperature for 2 to 4 hours, or overnight at room temperature 4 ℃. After the reaction, the C = n bond can be reduced by sodium borohydride. The conjugate can be purified by size exclusion chromatography or dialysis.

Storage condition:

-20 degrees freeze, can be packed, avoid repeated exposure to air, not to be preserved in solution.

Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.

Based on the business model of independent research and development, production and sales integration, the company's products have obvious price advantages compared with similar products on the market. In addition, we also provide professional product customization services.

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